Which layer of the epidermis is characterized by granules in cells?

The layer of the epidermis characterized by granules in cells is the stratum granulosum. This layer resides above the stratum spinosum and below the stratum lucidum (in thick skin) or the stratum corneum.

The granules found in the stratum granulosum are referred to as keratohyalin granules, which play a critical role in the process of keratinization. These granules contain proteins that help bind keratin filaments together, contributing to the formation of a tough barrier that protects underlying tissues. Additionally, the cells in this layer begin to lose their nuclei and become more flattened as they transition to the stratum corneum, which is the outermost layer of the skin.

Understanding the structure and function of the stratum granulosum is fundamental in aesthetics and dermatology because it is essential for maintaining skin hydration and overall health. In contrast, the stratum corneum consists primarily of dead keratinized cells, the stratum lucidum is typically found only in thick skin areas like the palms and soles, and the stratum basale is the deepest layer where cell division occurs. Each of these layers has a distinct role and composition, but the presence of gran