Which chemical peel has the smallest molecules?

Glycolic acid has the smallest molecules among the chemical peels listed, allowing it to penetrate the skin more effectively compared to other acids used in peels. This property makes glycolic acid particularly advantageous for treating superficial issues such as fine lines, uneven skin tone, and texture irregularities. Its smaller molecular size translates to deeper and more thorough exfoliation, which can enhance the overall appearance of the skin.

In contrast, salicylic acid, while also effective, tends to be larger in its molecular structure and is primarily used for its ability to penetrate and exfoliate within pores, making it ideal for acne treatment rather than superficial skin concerns. Jessner's solution, a blend of different acids, has medium-sized molecules that provide intermediate exfoliation. TCA, or trichloroacetic acid, has larger molecules that are generally used for deeper peels, targeting more significant skin issues but with less penetration than glycolic acid. Therefore, glycolic acid's unique characteristic of small molecular size sets it apart for targeted and effective superficial skin treatments.