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Pregnancy is a recognized contraindication for sclerotherapy because the treatment involves injecting a solution into the affected veins, which may pose risks to the developing fetus. During pregnancy, the body's circulation and the vascular system undergo significant changes, which could potentially lead to complications. There is also a lack of research on the safety of sclerotherapy in pregnant women, making it prudent to avoid the procedure during this time to protect both the mother and the unborn child.

Obesity, allergies, and high blood pressure, while they may raise considerations for patients undergoing various medical procedures, do not constitute absolute contraindications for sclerotherapy. For instance, obese patients might still qualify for treatment, and certain allergic reactions can be managed with pre-treatment assessments. High blood pressure is a condition to monitor but does not automatically prohibited the procedure. Therefore, the distinction regarding pregnancy is important for both patient safety and clinical practice.

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